A comprehensive set of hemodynamic parameters, blood gases and hemoglobin levels during spinal cord injury procedure followed by weekly assessments of locomotor and bladder function recovery with survival histology data from 334 rats in the MASCIS trial
DOI:10.34945/F5V884
DATASET CITATION
Nielson J. L., Liu A. W., Guandique C. F., Tovar C. A., Young W., Beattie M. S., Bresnahan J. C., Ferguson A. R. (2021) A comprehensive set of hemodynamic parameters, blood gases and hemoglobin levels during spinal cord injury procedure followed by weekly assessments of locomotor and bladder function recovery with survival histology data from 334 rats in the MASCIS trial. ODC-SCI:567 http://doi.org/10.34945/F5V884
ABSTRACT
STUDY PURPOSE: To describe the application of topological data analysis (TDA) for data-driven discovery in preclinical spinal cord injury (SCI) data sets mined from the Visualized Syndromic Information and Outcomes for Neurotrauma-SCI (VISION-SCI) repository.
DATA COLLECTED: This dataset contains MASCIS OSU trial subjects (N=334) for all measures of survival, histology, perioperative vitals and blood gases, functional recovery, bladder health and weight over 1–6 weeks post SCI.
DATA USAGE NOTES:
KEYWORDS
Topological Data Analysis; Spinal Cord Injury; data-driven discovery; FAIR data; Data recovery
PROVENANCE / ORIGINATING PUBLICATIONS
Topological data analysis for discovery in preclinical spinal cord injury and traumatic brain injury.. doi:10.1038/ncomms9581.
This paper reports the application of Topological Data Analysis for discovery in the presented dataset (Fig. 6a)
Development of a database for translational spinal cord injury research.. doi:10.1089/neu.2014.3399..
This paper reports the primary effort on data curation and database reconstruction of this MASCIS dataset along with other recovered datasets from multiple labs.
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DATASET INFO
Contact: Ferguson Adam R (adam.ferguson@ucsf.edu)
Lab: Ferguson Lab
ODC-SCI Accession:567
Records in Dataset: 334
Fields per Record: 80
Last updated: 2021-03-03 (See changelog)
Date published: 2021-03-03
Downloads: 22
Files: 2
LICENSE
Creative Commons Attribution License (CC-BY 4.0)
FUNDING AND ACKNOWLEDGEMENTS
Craig H. Neilsen Foundation Grant 224308, National Institutes of Health (NIH) NS067092 (A.R.F.), NS069537 (A.R.F), NS038079 (J.C.B. and M.S.B.), NS031193 and AG032518 (M.S.B. and J.C.B.), NS079030 (J.L.N.), NS032000 (W.Y.; M.S.B. site PI, multicentre study); NYSCoRE CO19772, Department of Defense (DoD) W81XWH-10-1-0910 (M.S.B.) and W81XWH-13- 1-0297 (M.S.B.), Wings for Life Foundation WFLUS008/12 and WFLUS006/ 14 (A.R.F.)
CONTRIBUTORS
- Nielson, Jessica L L.
- Department of Neurosurgery, Brain and Spinal Injury Center, University of California, San Francisco, 1001 Potrero Avenue, Building 1, Room 101, San Francisco, California 94143, USA.
- Liu, Aiwen W W.
- Department of Neurosurgery, Brain and Spinal Injury Center, University of California, San Francisco, 1001 Potrero Avenue, Building 1, Room 101, San Francisco, California 94143, USA.
- Guandique, Cristian F F.
- Department of Neurosurgery, Brain and Spinal Injury Center, University of California, San Francisco, 1001 Potrero Avenue, Building 1, Room 101, San Francisco, California 94143, USA.
- Tovar, C Amy A.
- Department of Neuroscience, Ohio State University, 460 West 12th Avenue, 670 Biomedical Research Tower, Columbus, Ohio 43210, USA.
- Young, Wise
- Department of Cell Biology and Neuroscience, W.M. Keck Center for Collaborative Neuroscience, Rutgers University, Piscataway, New Jersey 08854, USA.
- Beattie, Michael S S.
- Department of Neurosurgery, Brain and Spinal Injury Center, University of California, San Francisco, 1001 Potrero Avenue, Building 1, Room 101, San Francisco, California 94143, USA.
- Bresnahan, Jacqueline C C.
- Department of Neurosurgery, Brain and Spinal Injury Center, University of California, San Francisco, 1001 Potrero Avenue, Building 1, Room 101, San Francisco, California 94143, USA.
- Keller, Anastasia V.
- Brain and Spinal Injury Center (BASIC), Department of Neurological Surgery, University of California San Francisco, San Francisco, California, United States of America
- Ferguson, Adam R R. [ORCID:0000-0001-7102-1608]
- Brain and Spinal Injury Center (BASIC), Department of Neurological Surgery, University of California San Francisco, San Francisco, California, United States of America. adam.ferguson@ucsf.edu
- Torres-Espin, Abel
- Brain and Spinal Injury Center (BASIC), Department of Neurological Surgery, University of California San Francisco, San Francisco, California, United States of America
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