Trunk kinematic and center of pressure displacement time series data during transcutaneous lumbosacral spinal cord stimulation and passive pelvic tilt in human pediatric participants with trunk control impairments due to cervical or thoracic spinal cord injury (pilot clinical trial NCT03975634)

DOI:10.34945/F5NC7X

DATASET CITATION

Keller A., Singh G., Joel S., Ugiliweneza B., D'Amico J., Gerasimenko Y., Behrman A. (2021) Trunk kinematic and center of pressure displacement time series data during transcutaneous lumbosacral spinal cord stimulation and passive pelvic tilt in human pediatric participants with trunk control impairments due to cervical or thoracic spinal cord injury (pilot clinical trial NCT03975634). ODC-SCI:620 http://doi.org/10.34945/F5NC7X

ABSTRACT

STUDY PURPOSE: This was a pilot clinical trial that established the safety and feasibility of transcutaneous lumbosacral electrical spinal cord stimulation (scTS) to augment upright sitting posture and trunk control in children with spinal cord injury.

DATA COLLECTED: The feasibility of stimulation to potentiate upright sitting posture was assessed using trunk kinematics (degrees of flexion/extension in cervical, thoracic and lumbar trunk segments) and center of pressure displacement (the change in distance in mediolateral and anteroposterior directions as stimulation intensity was increased as well as during passive pelvic tilt without stimulation. 3D Kinematics (angular excursions) were measured using MVN BIOMECH Awinda MTW2-3A7G6 sensors (Xsens Technologies B.V. Enschede, Netherlands). The data was sampled at 60Hz and collected in MVN: 2019.2.1 software (XML format), mean flexion/extension angles (generated using a Kalman filter (Xsens Kalman Filter, XKF) from a 3D reconstruction of body segment position of trunk segments was calculated during at least 10 seconds of stable baseline sitting prior to stimluation and for when the participant was sitting with transcutaneous spinal stimulation on; center of pressure (COP) displacements were measured using force plate (Burtec, FP4060-NC-1000). Mean normalized COP was quantified as a change from COP values acquired during 10 seconds of baseline sitting to the COP values during sitting with individualized optimal transcutaneous stimulation intensity that induced upright posture.

CONCLUSIONS:

KEYWORDS

transcutaneous lumbosacral spinal cord stimulation; pediatric spinal cord injury; trunk control; kinematics

PROVENANCE / ORIGINATING PUBLICATIONS

• Anastasia Keller, Goutam Singh, Joel H. Sommerfeld, Molly King, Parth Parikh, Beatrice Ugiliweneza, Jessica D’Amico, Yury Gerasimenko & Andrea L. Behrman. Noninvasive spinal stimulation safely enables upright posture in children with spinal cord injury. Nat Commun 12, 5850 (2021). DOI:10.1038/s41467-021-26026-z.

NOTES

DATASET INFO

Contact: Behrman Andrea (andrea.behrman@louisville.edu)

Lab: Andrea Behrman

ODC-SCI Accession:620

Records in Dataset: 70317

Fields per Record: 41

Last updated: 2021-08-13

Date published: 2021-08-13

Downloads: 52

Files: 2

LICENSE

Creative Commons Attribution License (CC-BY 4.0)

FUNDING AND ACKNOWLEDGEMENTS

NIH/NCNM4R P2CHD086844

CONTRIBUTORS

Keller, Anastasia [ORCID:0000-0002-7919-8931]

University of California, San Francisco

Singh, Goutam [ORCID:0000-0002-3382-2321]

University of Louisville

Joel, Sommerfeld

University of Louisville

Ugiliweneza, Beatrice [ORCID:0000-0001-7334-6924]

University of Louisville

D'Amico, Jessica [ORCID:0000-0002-3487-0712]

University of Louisville

Gerasimenko, Yury [ORCID:0000-0003-1229-2410]

University of Louisville

Behrman, Andrea [ORCID:0000-0003-1859-8787]

University of Louisville